The Rising Incidence of Allergic Contact Dermatitis to Acrylates - Our experience confirms the worldwide changing landscape of rising (meth)acrylate sensitization in nail technicians and nail products users with ACD. Efforts to improve prevention are needed, and clinicians should have a high index for suspicion in this occupational group.

Allergic contact dermatitis caused by (meth)acrylates in long-lasting nail polish - are we facing a new epidemic in the beauty industry? - Most common allergens are 2-hydroxypropyl methacrylate, 2-hydroxyethyl methacrylate, and tetrahydrofurfuryl methacrylate

Sensitization to acrylates is a common adverse reaction to artificial fingernails - HPMA & HEMA monomers when used in sculpting artificial nails are important contact and occupational sensitizers that can produce cross-reactions with other acrylic compounds and trigger allergic reactions when re-exposure occurs in a different setting. i.e when used in dentistry 

Contact allergy resulting from the use of acrylate nails is increasing in both users and those who are occupationally exposed - Highlights how those who are in continued use of acrylate monomers such as HPMA & HEMA are at much greater risk of developing ACD.

Allergic contact dermatitis caused by 2-hydroxyethyl methacrylate and ethyl cyanoacrylate contained in cosmetic glues among hairdressers and beauticians who perform nail treatments and eyelash extension as well as hair extension applications: A systematic review - It was found that beauticians who perform nail treatments are subjected to a substantially higher risk of developing contact allergy against HEMA—representing a marker allergen within the group of (meth)acrylates (HPMA EMA etc...), compared with other people not working as beauticians. Clear evidence provided. 

[Sensitization to acrylates caused by artificial acrylic nails: review of 15 cases] - Acrylate monomers (HPMA & HEMA) used for sculpting nails are important sensitizers for contact and occupational dermatitis. The most important consideration is primary and secondary prevention. 

Acrylates as a significant cause of allergic contact dermatitis: new sources of exposure - This suggests that new policies to regulate usage of Acrylate monomers (HPMA & HEMA) chemicals for aesthetic procedures should be stricter. The awareness of a potential risk of sensitization to acrylates and available preventive measures need to be broadened particularly among workers of beauty industries during their apprenticeship. The new significant trend is allergic contact dermatitis. Patch tests are considered to be the gold standard in establishing diagnosis. It is required to include both HEMA and HPMA in the baseline series.

Allergic contact dermatitis caused by nail acrylates in Europe. An EECDRG study - 

Nail cosmetics were responsible for the majority of ACD cases caused by acrylates, affecting nail beauticians and consumers, and therefore calling for stricter regulation and preventive measures.


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